However, do you know you can also open Excel file with a web browser? You must know now and you can go to have a try. You know that you can open various kinds of files like Excel file in native external applications. To rescue your lost Excel files, you can use MiniTool Software. You can choose one based on your own situation. To solve this issue, we will show you three methods in this post. You may encounter the web browser won’t open Excel file issue when you want to open your Excel file with Google Chrome, Firefox, Internet Explorer, etc.